Exuberant Ca(2+) Signaling in Neutrophils: A Cause for Concern.
نویسنده
چکیده
Under inflammatory conditions after burn/trauma injuries, circulating neutrophils are frequently hyperactive, contributing to excessive superoxide production and related tissue damage. Although normal neutrophil activation is cooperatively controlled by Ca(2+)-independent and Ca(2+)-linked signaling pathways, exuberant Ca(2+)-linked signaling appears to cause neutrophil hyperactivation in the injury conditions.
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عنوان ژورنال:
- News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society
دوره 15 شماره
صفحات -
تاریخ انتشار 2000